Insulin-like Growth Factors

Insulin-like Growth Factors

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... to and activation of the IGF-IR [5]. a tyrosine kinase receptor that forms homodimers consisting of two alpha subunits and two beta subunits. ... ing both the IGF-IR and IR in vitro. and more recently. the existence of hybrid receptors has been verified in vivo [6-12]. ... Moreover. tissues analyzed for endogenous hybrid receptor formation contain between 40-90% of the total 0888-6008/02/$ 8.00 Ac 2003 - IOS Press. All rights reserved IGF-IR present in the form of the hybrid receptor [7.

Title:Insulin-like Growth Factors
Author: Douglas Yee
Publisher:IOS Press - 2004

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